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SciGene Inc microarray oven
KEGG-pathway Comparison of Gene Expression Changes in Human colon cancer and Mouse Model. Displayed here are the murine gene expression patterns derived from murine mRNA <t>microarray</t> analysis from the late-transformed colon cell lines, which were compared with human CRC specific genes as listed in the KEGG pathway. We have superimposed the directionality of the gene expressions of the colon-specific mouse genes onto the human genes using the red shading within the boxes to indicate upregulation, and green shading for downregulation. The red boarders correspond to genes upregulated in the human colon cancer pathway; green boarders reveal those that are downregulated. No shading indicates that no change occurred in expression of the colon cancer-specific mouse genes relative to normal uncultured mouse epithelial cells. Two tumor suppressors associated with human colon cancer, Apc and Dcc were both downregulated in the mouse model. Ccn1b, Smad3, and Tgfb1, which are upregulated in human CRC were also upregulated in the mouse. The two major differences between the two species are for the genes Bcatenin and ERK, both of which are upregulated in human colon cancers, but downregulated in the transformed murine colon epithelial cells.
Microarray Oven, supplied by SciGene Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
microarray oven - by Bioz Stars, 2026-08
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SciGene Inc microarray oven, 777
KEGG-pathway Comparison of Gene Expression Changes in Human colon cancer and Mouse Model. Displayed here are the murine gene expression patterns derived from murine mRNA <t>microarray</t> analysis from the late-transformed colon cell lines, which were compared with human CRC specific genes as listed in the KEGG pathway. We have superimposed the directionality of the gene expressions of the colon-specific mouse genes onto the human genes using the red shading within the boxes to indicate upregulation, and green shading for downregulation. The red boarders correspond to genes upregulated in the human colon cancer pathway; green boarders reveal those that are downregulated. No shading indicates that no change occurred in expression of the colon cancer-specific mouse genes relative to normal uncultured mouse epithelial cells. Two tumor suppressors associated with human colon cancer, Apc and Dcc were both downregulated in the mouse model. Ccn1b, Smad3, and Tgfb1, which are upregulated in human CRC were also upregulated in the mouse. The two major differences between the two species are for the genes Bcatenin and ERK, both of which are upregulated in human colon cancers, but downregulated in the transformed murine colon epithelial cells.
Microarray Oven, 777, supplied by SciGene Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/microarray+oven/pmc03731808-108-9-11?v=SciGene+Inc
Average 90 stars, based on 1 article reviews
microarray oven, 777 - by Bioz Stars, 2026-08
90/100 stars
  Buy from Supplier

90
Hybex Innovations microarray hybridization chamber
KEGG-pathway Comparison of Gene Expression Changes in Human colon cancer and Mouse Model. Displayed here are the murine gene expression patterns derived from murine mRNA <t>microarray</t> analysis from the late-transformed colon cell lines, which were compared with human CRC specific genes as listed in the KEGG pathway. We have superimposed the directionality of the gene expressions of the colon-specific mouse genes onto the human genes using the red shading within the boxes to indicate upregulation, and green shading for downregulation. The red boarders correspond to genes upregulated in the human colon cancer pathway; green boarders reveal those that are downregulated. No shading indicates that no change occurred in expression of the colon cancer-specific mouse genes relative to normal uncultured mouse epithelial cells. Two tumor suppressors associated with human colon cancer, Apc and Dcc were both downregulated in the mouse model. Ccn1b, Smad3, and Tgfb1, which are upregulated in human CRC were also upregulated in the mouse. The two major differences between the two species are for the genes Bcatenin and ERK, both of which are upregulated in human colon cancers, but downregulated in the transformed murine colon epithelial cells.
Microarray Hybridization Chamber, supplied by Hybex Innovations, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/microarray+oven/10__1158_slash_0008___5472__can___08___3028-80-7-6?v=Hybex+Innovations
Average 90 stars, based on 1 article reviews
microarray hybridization chamber - by Bioz Stars, 2026-08
90/100 stars
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KEGG-pathway Comparison of Gene Expression Changes in Human colon cancer and Mouse Model. Displayed here are the murine gene expression patterns derived from murine mRNA microarray analysis from the late-transformed colon cell lines, which were compared with human CRC specific genes as listed in the KEGG pathway. We have superimposed the directionality of the gene expressions of the colon-specific mouse genes onto the human genes using the red shading within the boxes to indicate upregulation, and green shading for downregulation. The red boarders correspond to genes upregulated in the human colon cancer pathway; green boarders reveal those that are downregulated. No shading indicates that no change occurred in expression of the colon cancer-specific mouse genes relative to normal uncultured mouse epithelial cells. Two tumor suppressors associated with human colon cancer, Apc and Dcc were both downregulated in the mouse model. Ccn1b, Smad3, and Tgfb1, which are upregulated in human CRC were also upregulated in the mouse. The two major differences between the two species are for the genes Bcatenin and ERK, both of which are upregulated in human colon cancers, but downregulated in the transformed murine colon epithelial cells.

Journal: Genes, chromosomes & cancer

Article Title: Novel Mouse Model Recapitulates Genome and Transcriptome Alterations in Human Colorectal Carcinomas

doi: 10.1002/gcc.22426

Figure Lengend Snippet: KEGG-pathway Comparison of Gene Expression Changes in Human colon cancer and Mouse Model. Displayed here are the murine gene expression patterns derived from murine mRNA microarray analysis from the late-transformed colon cell lines, which were compared with human CRC specific genes as listed in the KEGG pathway. We have superimposed the directionality of the gene expressions of the colon-specific mouse genes onto the human genes using the red shading within the boxes to indicate upregulation, and green shading for downregulation. The red boarders correspond to genes upregulated in the human colon cancer pathway; green boarders reveal those that are downregulated. No shading indicates that no change occurred in expression of the colon cancer-specific mouse genes relative to normal uncultured mouse epithelial cells. Two tumor suppressors associated with human colon cancer, Apc and Dcc were both downregulated in the mouse model. Ccn1b, Smad3, and Tgfb1, which are upregulated in human CRC were also upregulated in the mouse. The two major differences between the two species are for the genes Bcatenin and ERK, both of which are upregulated in human colon cancers, but downregulated in the transformed murine colon epithelial cells.

Article Snippet: The microarrays were hybridized in a rotisserie Microarray Oven (Model 777 SciGene, Sunnyvale, CA) at 658C and speed of 10 rpm for 40 hr.

Techniques: Expressing, Derivative Assay, Microarray, Transformation Assay